I've used EB Stone 5-5-5 (organic) with good success. However, I tried synthetic with 5-10-10 or 10-10-10 and found for some plants, like broccoli, cauliflower, cabbage, corn, eggplant and some others, I get healthier looking, bigger plants and bigger harvest. Seems like lettuce, and other smaller plants do better with the organic. For tomatoes, I haven't seen much difference.